Abstract #3800

Exploration of interstitial fibrosis in chronic kidney disease by diffusion-relaxation correlation spectrum MR imaging

Fang Liu¹, Wentao Hu², Yongming Dai², Minfang Zhang³, and Yan Zhou¹

¹Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, ²MR Collaboration, Central Research Institute, United Imaging Healthcare, Shanghai, China, ³Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

Synopsis

Keywords: Kidney, Diffusion/other diffusion imaging techniques

Non-invasive evaluation of interstitial renal fibrosis would help monitoring chronic kidney disease (CKD) progression and prognosis prediction. This study was aimed to evaluate renal interstitial fibrosis by diffusion relaxation correlated spectrum imaging (DR-CSI). Correlation was found between DR-CSI volume fractions and interstitial fibrosis level (IFL). V_B illustrated best diagnostic performance among MRI indicators. We suggest DR-CSI is of potential value in the evaluation of renal interstitial fibrosis.

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