Abstract #3803

A NEW METHOD TO ANALYSE RENAL PERFUSION: A PROOF OF CONCEPT

Luis Carlos Sanmiguel Serpa^1,2,3, Pieter De Visschere^1,2, Marijn Speeckaert^4,5, and Pim Pullens^3,6

¹Radiology, Ghent University Hospital, Ghent, Belgium, ²Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium, ³Ghent Institute of Functional and Metabolic Imaging, Ghent University, Ghent, Belgium, ⁴Nephrology, Ghent University Hospital, Ghent, Belgium, ⁵Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium, ⁶6IBiTech– Medisip, Ghent University, Ghent, Belgium

Synopsis

Keywords: Kidney, Arterial spin labelling

To date, renal ASL MRI images are analysed with methods that may underestimate renal perfusion or that may be observer-dependent. In this study, we implemented two analysis methods that take into account the complex morphology of the kidney. One analyses the kidney progressively, from the cortex to the medulla, and the second one, a new algorithm analyses the kidney in radial sections. Our results show that perfusion values change across the kidney and that healthy subjects have higher perfusion values. This study shows the importance of using more robust analysis on kidney ASL MRI images.

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