Keywords: Kidney, Kidney
We investigated quantitative T2 mapping as an MRI biomarker for disease progression in mouse models of autosomal dominant polycystic kidney disease and its correlation with kidney function. Our results show a good correlation between the fraction of the kidney tissue with elevated T2 and cyst load quantified by histology. There was also a good correlation between high T2 values and kidney function decline indicated by reduced glomerular filtration rates.
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