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Abstract #3812

Assessment of renal lipid deposition and abnormal oxygen metabolism of type 2 diabetes mellitus based on mDixon-Quant

Chun Yang1,2, Yishi Wang3, Wei Li1, and Yuxin Wang1,2
1The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China, 2Shandong First Medical University, Jinan, China, 3Philips Healthcare, Beijing, China

Synopsis

Keywords: Kidney, Endocrine, mDixon-Quant, type 2 diabetes mellitus, renal functionmDixon-Quant adopts a multi-echo 3D fast GRE sequence that can be used to obtain fat fraction, T2* and R2* mapping in a single breath hold. The variation of deoxyhemoglobin in the kidney can reflect the oxygen metabolism in patients with diabetic nephropathy under pathological and physiological conditions. FF maps can be used for fat quantification. mDixon-Quant provides the assessment both fat metabolism and oxygen metabolism of the kidney at the same time and may be valuable in detecting changes in renal function and pathology.

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Keywords