Keywords: Kidney, CEST & MTRenal tumors are often containing lipid components, ischemic-hypoxia and hemorrhage. These components can be reflected by the proton density fat fraction (PDFF) and R2* levels of the mDIXON_Quant. Amide proton transfer-weighted (APTw) imaging has made breakthroughs in tumor research, however, its signal intensity is affected by many factors. This study focused on the effect of PDFF and R2* values on APTw values in renal tumors. The preliminary results showed that renal tumor APT values were correlated with PDFF and R2* values. Thus, precision APTw imaging studies of renal tumors need to consider the effects of differential composition.
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