Keywords: Flow, Cardiovascular, Marfan Syndrome, Loeys-Dietz Syndrome, Vascular Ehlers-Danlos syndromeQuantitative overview of 4D flow derived aortic hemodynamic parameters such as kinetic energy, peak velocity, and pulse wave velocity in a cohort of pediatric patients with connective tissue disorders such as Marfan Syndrome (MFS), Loeys-Dietz Syndrome (LDS), and Vascular Ehlers-Danlos Syndrome (EDS), using a fully automated pipeline. A statistically significant trend of increased pulse wave velocity - an important measure of vessel stiffness, with increasing age was observed for this cohort. No association was found between PWV and all mean aortic diameters when controlled for age.
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