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Abstract #3833

Interval Changes in 4D Flow-Derived Hemodynamic Parameters Stratify Type B Aortic Dissection Patients and Correlate with 2D Through-Plane Flow

Josh Engel1, Ozden Kilinc1, Justin Baraboo2, Elizabeth Weiss1,2, Christopher Mehta3, Andrew Hoel4, S. Chris Malaisrie3, Michael Markl2, and Bradley Allen1
1Radiology, Northwestern University, Chicago, IL, United States, 2Biomedical Engineering, Northwestern University, Chicago, IL, United States, 3Cardiac Surgery, Northwestern Medicine, Chicago, IL, United States, 4Vascular Surgery, Northwestern Medicine, Chicago, IL, United States

Synopsis

Keywords: Vessels, Velocity & Flow, Aortic Dissection, 4D FlowWe investigated whether changes in 4D flow-derived hemodynamic parameters stratified type B aortic dissection patients and sought to validate a 4D flow-derived 2D planar false lumen flow method. Patient scans with baseline and follow-up 4D flow at least 120 days apart were manually segmented into true and false lumens. Voxel-wise parametric maps and 2D forward and reverse flow in the descending aorta were calculated. Changes in voxel-wise hemodynamic parameters significantly correlated with aortic growth rate, with changes in false lumen reverse flow as the most robust parameter. 2D planar flow correlated with voxel-wise flow, but not aortic growth.

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Keywords