Abstract #3834

Ventricular flow analysis and its Association with cadiac function and structure of hypertrophic cardiomyopathy: 4D flow CMR study

Yuying Chen¹, Yang Peng¹, Yu Feng¹, Jun Yuan¹, Lin Peng¹, Mengzhu Wang², and Ning Jin³

¹The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²MR Scientific Marketing, Siemens Healthineers Ltd., Guangzhou, China, ³Siemens Medical Solutions USA, Inc. Customer Solutions Group，Siemens Healthineers, MR Scientific Marketing, Siemens Healthineers Ltd., Chicago, IL, United States

Synopsis

Keywords: Cardiomyopathy, Cardiomyopathy, 4D flowThis study aimed to investigate the potential of ventricular flow parameters derived from four‑dimensional (4D) flow cardiovascular magnetic resonance (CMR) to accurately support assessment of hypertrophic cardiomyopathy (HCM). Our results show that reduced left ventricular (LV) residual volume was associated with LV dysfunction. Higher LV retained inflow and lower delayed ejection inflow were observed in obstructive HCM patients. Flow components and kinetic energy correlated significantly with LV functional and remodelling CMR parameters. These findings suggest that 4D flow CMR may be potential method to explain the relationship between hemodynamic and pathophysiological changes in HCM.

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