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Abstract #3854

Slope of the spectrum of low-frequency BOLD signal relation to the connectivity strength

Kazuhiro Nakamura1 and Toshibumi Kinoshita1
1Research Institute for Brain and Blood Vessels Akita, Akita, Japan

Synopsis

Keywords: fMRI (resting state), fMRI (resting state), spectrum analysisFor the valuation of BOLD fluctuations, we have investigated the slope of the spectrum (SLOPE) to exclude the respiratory and heartrate fluctuation. Functional connectivity (ROI to ROI) was evaluated by Conn v19.b software. The SLOPE was evaluated in the frequency range of 0.01 – 0.1Hz. Maximum connectivity in each ROI correlated well with the value of SLOPE, but the mean connectivity did not. Therefore, it will be possible to evaluate the strength of connectivity of rs-fMRI by evaluating SLOPE.

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