Abstract #3858

Efficient Myocardial Spectroscopy combining Metabolite-Cycling with Respiratory Bellows at 3T

Fabian Bschorr¹, Tobias Speidel¹, Niklaus Zoelch^2,3, Andreas Hock⁴, Alireza Abaei⁵, and Volker Rasche¹

¹Ulm University Hospital, Ulm, Germany, ²Zurich University Hospital of Psychiatry, University of Zurich, Zurich, Switzerland, ³Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland, ⁴Zurich University of Applied Sciences, Wädenswil, Switzerland, ⁵Core Facility Small Animal Imaging (CF-SANI), University of Ulm, Ulm, Germany

Synopsis

Keywords: Spectroscopy, CardiovascularDespite its diagnostic values^1-4, the application of cardiac spectroscopy (CMRS) in clinical routine is generally limited by technical challenges and long scan times. A protocol for CMRS is proposed using metabolite-cycling, local, ECG-triggered shimming, ECG-triggering and a respiratory bellows. The protocol is evaluated in a volunteer cohort and provides myocardial triglyceride content (MTGC) quantification results that correlate well intrasession- (r=0.98, p<0.001) and intersession-wise (r=0.95, p<0.001). Thus, a good repeatibility and technical stability for the quantification of MTGC could be achieved with an average scan time of 440s at 3T.

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