Abstract #3859

Comparison of Magnetic Resonance Spectroscopy Data Acquired with Hybrid PET-MRI and Standalone MRI Scanners

Aditya Bhattacharya¹, Benjamin B. Risk², and Candace C. Fleischer^3,4

¹Neuroscience, Georgia Institute of Technology, Atlanta, GA, United States, ²Biostatistics and Bioinformatics, Emory University, Atlanta, GA, United States, ³Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States, ⁴Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States

Synopsis

Keywords: Spectroscopy, PET/MRMagnetic resonance spectroscopy (MRS) is a powerful tool for quantifying metabolite concentrations, but spectral quality has not been thoroughly explored in hybrid MRI scanners. Using repeated measurements in a brain phantom and healthy volunteer, we determined the reproducibility and accuracy of MRS data on two systems, a hybrid GE PET-MRI (3.0 T) and Siemens 3.0 T MRI. Spectra acquired using the PET-MRI scanner produced metabolite concentrations with higher accuracy and lower variance across repeated measurements compared to the standalone MRI, suggesting spectral quality is not hindered by the hybrid system.

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