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Abstract #3870

Parallel Proton and Deuterium Metabolic Imaging

Yanning Liu1, Chathura Kumaragamage1, Terry W. Nixon1, Scott McIntyre1, Henk De Feyter1, and Robin A. de Graaf1
1Yale University, New Haven, CT, United States

Synopsis

Keywords: Deuterium, Deuterium, DMI

1H MRSI and DMI can provide crucial metabolic information to facilitate evaluations of neurological diseases. In this work, we applied interleaved 1H/2H methodology to achieve time-efficient, parallel 1H MRSI and DMI acquisition. We first describe the necessary sequence adjustments for both nuclei, including the re-optimization of the VAPOR water suppression scheme and the incorporation of a 2H equilibrium pulse. Phantoms were then used to demonstrate that high quality 1H MRSI and DMI data can be acquired in parallel. The interleaved 1H MRSI-DMI sequence is compatible with other interleaved MRI-DMI sequences and can be implemented for a complete MRI-DMI protocol.

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