Meeting Banner
Abstract #3874

Comparison the metabolism of [2H2]glucose,[2H7]glucose and [2H5]glucose in rat C6 glioma cells

Jiawen Yuan1,2, Yi Fang1, Qian Wan1, Chao Zou1,3, Xiaoliang Zhang4, Xin Liu1,3, Hairong Zheng1,3, and Ye Li1,3
1Lauterbur Imaging Research Center, Shenzhen Institute of Advanced Technology, Chinese Acamedy of Sciences, Shenzhen, China, 2Southern University of Science and Technology, Shenzhen, China, 3Key Laboratory for Magnetic Resonance and Multimodality Imaging of Guangdong Province, Shenzhen, China, 4Department of Biomedical Engineering, State University of New York at Buffalo, Buffalo, NY, United States

Synopsis

Keywords: Deuterium, DeuteriumDeuterium MRS(I) has emerged as a novel metabolic imaging method, which can effectively reflect the increased aerobic glycolysis of tumors. Recently, [2,3,4,6,6-2H5] glucose has been shown to be a cost-effective deuterium-labeled substrate for studying glycolysis in tumors. However, the effects of different deuterium-labeled substrates on metabolism require further comparison. In this study, we compared the differences between [6,6-2H2] glucose, [1,2,3,4,5,6,6’-2H7] glucose, and [2,3,4,6,6-2H5] glucose in rat C6 glioma cells.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract Presentation Video

Keywords