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Abstract #3897

High permittivity ceramics for improving detection of fMRI activation at 1.5T

Vladislav Koloskov1, Mikhail Zubkov1, Georgiy Solomakha1, Viktor Puchnin1, Anatoliy Levchuk1,2, Alexander Efimtcev1,2, Irina Melchakova1, and Alena Shchelokova1
1School of Physics and Engineering, ITMO University, St. Petersburg, Russian Federation, 2Department of Radiology, Federal Almazov North-West Medical Research Center, St. Petersburg, Russian Federation

Synopsis

Keywords: Hybrid & Novel Systems Technology, Hybrid & Novel Systems Technology, high permittivity materials, SNR enhancementWe show that high permittivity materials (HPMs) can improve functional magnetic resonance imaging (fMRI) at 1.5T, increasing the receive sensitivity of a commercial multi-channel head coil. Both numerical simulations and experiment showed ~25% improvement in the signal-to-noise ratio (SNR) of a commercial head coil in the areas of interest when HPM blocks were placed in proximity. This led to an increase in the detected motor cortex fMRI activation volume by an average of 56%, thus resulting in more accurate functional imaging at 1.5T.

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