Abstract #3937

Compressed Sensing MPRAGE accelerates automated voxel placement for 1-H MRS of the human brain

Stefano Tambalo¹, Sebastian Hübner¹, Francesca Saviola¹, Tobias Kober^2,3,4, and Jorge Jovicich¹

¹University of Trento, Trento, Italy, ²Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, ³Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁴LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

Synopsis

Keywords: Data Processing, SpectroscopyThe automated voxel placement (AVP) framework has been proposed to optimize accuracy and reproducibility in single-voxel brain proton spectroscopy. AVP is based on the affine transformation of brain coordinates from standard to subject-specific space defined on a 3D T1-weighted structural scan. Here we evaluate the robustness of the AVP approach by evaluating the displacement of voxel center coordinates across 3D T1w MPRAGE sequence variants, including compressed sensing (CS) accelerated protocols. We show that AVP gave small but significantly higher voxel displacements for MP2RAGE and CS-MP2RAGE. There were no significant differences between multi-echo MPRAGE (6 min) and CS-MPRAGE (1 min).

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.