Abstract #3951

Two Dimensional MRSI of Human Calf Muscle at 3T: Decoupling and NOE effects on PDE and total NAD

Rajakumar Nagarajan¹, Jane A Kent², and Gwenael Layec²

¹Human Magnetic Resonance Center, Institute for Applied Life Sciences, University of Massachusetts, Amherst MA, Amherst, MA, United States, ²Kinesiology, University of Massachusetts, Amherst MA, Amherst, MA, United States

Synopsis

Keywords: Data Acquisition, Spectroscopy

Using two-dimensional 31-phosphorus spectroscopic imaging (2D-MRSI) in human skeletal muscle, we have demonstrated that proton decoupling and nuclear Overhauser effect sequences improve the coefficient of variation and enhance the resolution of key metabolites in vivo.

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