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Abstract #3954

Comparison of uniform-density, variable-density and dual-density spiral samplings for multi-shot diffusion-weighted imaging

Guangqi Li1, Xiaodong Ma2, Sisi Li1, Xinyu Ye1, Peter Börnert3,4, Xiaohong Joe Zhou5, and Hua Guo1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, 3Radiology, C.J. Gorter Center for High-Field MRI, Leiden University Medical Center, Leiden, Netherlands, 4Philips Research, Hamburg, Germany, 5Center for MR Research and Departments of Radiology, Neurosurgery, and Biomedical Engineering, University of Illinois College of Medicine at Chicago, Chicago, IL, United States

Synopsis

Keywords: Data Acquisition, Diffusion Tensor ImagingDifferent multi-shot spiral sampling schemes have been developed for high-resolution DWI. However, the performances of these sampling strategies such as variable-density spiral (VDS), dual-density spiral (DDS) and uniform-density spiral (UDS) have not been compared comprehensively. In this study, we compare multi-shot UDS, VDS and DDS in brain DWI in terms of inter-shot phase error correction, overall image quality and SNR performance. Both theoretical analysis and in-vivo results demonstrate that UDS exhibits the best off-resonance performance among the three spiral sampling patterns. Additionally, UDS achieves the highest SNR in diffusion imaging over the VDS and DDS acquisitions.

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