Keywords: Data Acquisition, Diffusion/other diffusion imaging techniquesNavigator-free multi-shot spiral and EPI acquisitions have been developed to achieve 2D high-resolution diffusion imaging. In this study, we investigated the off-resonance effects of spiral and iEPI samplings with different partial Fourier factors based on a signal model. Moreover, the SNR performances of the two multi-shot acquisitions at different resolutions and TEs were also explored. In summary, compared with iEPI, spiral provides superior SNR in multi-shot navigator-free DWI at various resolutions and TEs, even when the TE of spiral acquisition is slightly longer than that of iEPI. However, off-resonance correction for spiral sampling with ultra-long readout durations is more challenging.
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