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Abstract #3958

AcceleraTed deep-LeArning for model-free and multi-Shell (ATLAS) DWI

Phillip Andrew Martin1, Maria Altbach2,3, and Ali Bilgin1,2,3,4
1Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ, United States, 2Department of Biomedical Engineering, University of Arizona, Tucson, AZ, United States, 3Department of Medical Imaging, University of Arizona, Tucson, AZ, United States, 4Department of Applied Mathematics, University of Arizona, Tucson, AZ, United States

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Diffusion/other diffusion imaging techniques

In this work, we aim to accelerate diffusion weighted MRI (dMRI) by predicting diffusion -weighted images (DWIs) across different shells using deep learning (DL), while remaining independent of a diffusion-model constraint. The proposed approach enables the predictions of unacquired DWIs in multiple shells from a small set of acquired DWIs from a given shell. This relaxes the need for applying multiple diffusion gradient weightings for obtaining a fully-acquired dataset over multiple shells. Without the constraint of a diffusion model, accurate diffusion metrics over multiple diffusion models can potentially be obtained by acquiring a small number of DWIs.

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Keywords