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Abstract #3987

Z-spectrum Imaging of Bowel Wall Fibrosis in Crohn's Disease

Nabeelah Jinnah1, Olivier Mougin1, Penny Gowland1, Caroline Hoad1, Lauren Gascoyne1, Christopher Clarke2, and Gordon Moran1
1University of Nottingham, Nottingham, United Kingdom, 2Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom

Synopsis

Keywords: Digestive, CEST & MTZ-spectrum imaging was performed on bowel wall from Crohn's disease patients, to determine it's potential as a method of determining the fibrotic component of scarred bowel wall. Results show that there is a difference between the MT amplitude and linewidth of healthy compared with strictured bowel wall. Future work will involve optimising a protocol to use as a imaging biomarker of the fibrosis within bowel wall in Crohn's disease.

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Keywords