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Abstract #3995

T2*BOLD for evaluating coronary arteries with hemodynamic changes in stable multivessel coronary artery disease

Lei Zhao1, Weibo Chen2, Yongyi Wang1, Song Xue1, and Lianming Wu1
1Renji Hospital, Shanghai, China, 2Philips Healthcare, Shanghai, China

Synopsis

Keywords: Vessels, Cardiovascular, T2*-mappingThis study used T2*BOLD and QFR to evaluate coronary arteries with hemodynamic changes in coronary artery disease. Fifty patients with at least 1 significant coronary artery stenosis (diameter stenosis >50%) and 21 healthy control subjects underwent coronary angiography combined with QFR measurements and CMR. The CMR protocol consisted of T2* mapping and resting perfusion, contrasted with QFR. QFR≤0.80 was considered to indicate the presence of hemodynamic obstruction. Our study revealed that T2* BOLD and QFR have good agreement in detecting hemodynamic changes of stenotic coronary arteries. T2* BOLD is superior to semiquantitative perfusion imaging in analyzing myocardial perfusion without stress.

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