Abstract #3997

Multiparametric 3D cardiac MR for simultaneous bright- and black-blood imaging and joint T1/T2 myocardial tissue mapping

Ivan Kokhanovskyi^1,2,3, Michael G Crabb², Karl P Kunze^2,4, Radhouene Neji^2,4, Carl Ganter¹, Donovan P Tripp², Carlos Castillo-Passi^2,5, Dimitrios C Karampinos¹, Claudia Prieto^2,5,6,7, and Rene M Botnar^2,3,5,6,7

¹Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany, ²School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ³Institute for Advanced Study, Technische Universität München, Garching, Germany, ⁴MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, ⁵Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile, ⁶Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁷Instituto de Ingeniería Biológica y Médica, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Heart, Data AcquisitionAccurate diagnosis of cardiac disease requires imaging with high spatial resolution and whole-heart coverage. Current clinical protocols acquire contrasts sequentially, in different 2D orientations during several breath-holds leading to long examination times and misregistration artifacts. To address these limitations, we present a novel free-breathing four-heartbeat sequence for simultaneous 3D whole-heart Assessment of Cardiovascular anaTomy via bright- and black-blood Imaging and T1/T2 myocardial tissue quantificatiON (ACTION). Sequence parameters are optimized with Bloch simulations to enhance the mapping sensitivity and to improve the quality of anatomical images. Primarily results in a standardized phantom and in-vivo show potential for comprehensive heart disease detection.

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