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Abstract #4006

Fast 3D free-breathing simultaneous T1 and T1ρ mapping for noncontrast myocardial tissue characterization at 3T

Haikun Qi1,2, Junpu Hu3, Jian Xu4, Jiayu Zhu3, René Rene Botnar5, Claudia Prieto5, and Peng Hu1,2
1ShanghaiTech University, Shanghai, China, 2Shanghai Clinical Research and Trial Center, Shanghai, China, 3United Imaging Healthcare, Shanghai, China, 4UIH America, Inc., Houston, TX, United States, 5School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Synopsis

Keywords: Myocardium, Tissue CharacterizationRelaxation parameters T1 and T1ρ have shown promising results for endogenous assessment of myocardial tissue. However, mapping of the whole moving heart is challenging. This study proposes a novel free-breathing joint T1 and T1ρ mapping technique with near-isotropic spatial resolution, whole left ventricle coverage and short acquisition time of 5-6min. A diaphragmatic navigator was leveraged for prospective motion correction and retrospective motion mitigation. The T1ρ preparation module was optimized to be robust to field inhomogeneities and applicable to 3T. Phantom results indicated good accuracy of the proposed technique, and in vivo feasibility was demonstrated in healthy subjects.

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