Abstract #4008

Texture analysis of area-at-risk based on T1-mapping associated with infarct characteristics following acute STEMI

Jiali Wang¹, Kai Xu¹, Chunfeng Hu¹, Yankai Meng¹, Shuguang Han¹, Peng Wu², Lu Han², and Yongzhou Xu³

¹The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China, ²Philips Healthcare, Shanghai, China, ³Philips Healthcare, Guangzhou, China

Synopsis

Keywords: Myocardium, Ischemia, T1 mappingTo assess the potential of texture analysis (TA) of area-at-risk (AAR) based on native T1 mapping in predicting the severity of injury in ST-segment elevation myocardial infarction (STEMI) patients. Cine, T1 mapping, and late gadolinium enhancement (LGE) images were analyzed to evaluate cardiac function, and scar characteristics. The predictive value of TA for adverse LV remodeling (ALVR) and large final infarct size was evaluated. Entropy and uniformity (parameters of TA) in AAR of T1 mapping were highly correlated with convalescent infarct size, uniformity independently predicted large final infarct size, however, TA of AAR was not associated with convalescent ALVR.

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