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Abstract #4010

Novel myocardial T1 analysis robust to transient longitudinal relaxation due to irregular heart rate variability in PCTIP

Yuta Endo1, Sanae Takahashi1, Haruna Shibo1, Kuninori Kobayashi1, Makoto Amanuma1, and Shigehide Kuhara1
1Department of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, Tokyo, Japan

Synopsis

Keywords: Myocardium, Relaxometry, Myocardial T1 mapping, PCTIPMyocardial T1 mapping by polarity-corrected inversion time preparation (PCTIP) is expected to reduce measurement underestimation compared to the MOLLI method. However, measurement precision is reportedly reduced, especially for heart-rate variability. We devised an analysis to overcome this problem in PCTIP and showed that it improved measurement accuracy at high heart rates. Conventional analysis has difficulty fitting to this complex T1 relaxation, resulting in less accurate and precise measurement of longer T1. T1 analysis of PCTIP using the proposed analysis showed the potential to achieve accurate and precise T1 measurements, even for irregular heart rate variability.

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