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Abstract #4026

Default Mode Network is Not Related to Similarly Vigilance Dependent Slow Rhythms

Vahid Khalilzad Sharghi1, Eric Maltbie1, Wen-Ju Pan1, Shella Keilholz1, and Kaundinya Gopinath1
1Emory University, Atlanta, GA, United States

Synopsis

Keywords: fMRI (resting state), Brain ConnectivitySeveral studies point to brain slow rhythms as the basis of rsfMRI signal. We recently reported that only vigilance/arousal dependent components of fMRI signal that are not specific to brain function networks (BFNs) decrease after suppression of slow rhythms, while BFNs increase in apparent strength. Default mode network (DMN) is a BFN that exhibits similar dependence on vigilance as slow rhythms. In this study, we examined the effects of slow rhythm suppression on the integrity of DMN. Our results show that DMN is not related to these rhythms and behaves just like other BFNs upon their suppression.

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Keywords