Abstract #4051

Increase in Fast-relaxing Sodium After a Brief Plantarflexion Exercise Detected by Multi-Echo UTE MRI and Biexponential Regression

Kwan-Jin Jung¹, Hsin-Yu Fang², Brad Sutton³, and Kenneth Wilund²

¹Biomedical Imaging Center, Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ²Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ³Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States

Synopsis

Keywords: Muscle, Relaxometry, Sodium, Muscle, ExerciseWe measured the exercise-induced change in fast and slow T2-relaxing sodium in calf muscles separately using a UTE sequence with multiple echoes. Three minutes of plantarflexion exercise resulted in an increase in the fast-relaxing sodium and no change in the slow-relaxing component. Based on the known physiology that muscle intracellular sodium increases during muscle contraction, the measured fast-relaxing sodium might represent muscle intracellular sodium. This finding is valuable in studying intra- and extracellular sodium separately.

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