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Abstract #4053

Axial diffusivity and kurtosis derived based on DWI reflect microstructure changes in patients with in stress urinary incontinence patients

Kun Ou1, Weiyn Vivian Liu2, and Kun Zhang1,3
1Department of Radiology, First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China, 2MR Research, GE Healthcare, Beijing, China, 3College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, ChangSha, China

Synopsis

Keywords: Muscle, Diffusion/other diffusion imaging techniques, Diffusion kurtosis imagingStress urinary incontinence (SUI) is the most common form of urinary incontinence. However, in patients with SUI, the pelvic floor muscles generally have no obvious radiographic abnormalities. This study applied diffusion-weighted imaging with different analysis models and found that patients with SUI had significantly lower FA and Da values based on gaussian-distributed water movement and higher values in the Ka based on non-gaussian-distributed water movement compared to the healthy volunteers. This study showed both DTI and DKI derived parameters can detect microstructure changes in the the pubic visceral muscle of the SUI patients.

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