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Abstract #4055

Intervertebral disc’s quantitative measurements from synthetic MR correlates with its degeneration and bone marrow fat fraction

Xiaochun Yuan1, Ze Li1, Min Fu1, Xiaochen Wei2, and Junrong Chen3
1Chengdu Sport University, Chengdu, China, 2GE Healthcare China, Beijing, China, 3Sichuan Province Orthopedic Hospital, Chengdu, China

Synopsis

Keywords: Muscle, Fat, Quantitative imaging, Lumbar disc herniationThe conventional Pfirrmann grading currently used to assess the degree of disc degeneration is a semi-quantitative assessment criterion. And the relationship between vertebral body bone marrow fat and disc degeneration needs further clarification. In this study, quantitative synthetic MR technique as well as fat quantification MR technique are used to investigate relationship between imaging markers and degeneration levels. Results indicates intervertebral discs’ quantitative T2, T1 and PD values are significantly different among Pfirrmann grading groups. Significant negative correlations are found between Pfirrmann grading and quantitative values. T1 and PD values have weak correlation with bone marrow fat fraction.

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