Abstract #4070

The Feasibility Study of Extraocular Muscle Volume in Patients with Myasthenia Gravis Based on 3D TOFMRA

Qin Zhou¹, Pei Chen¹, Zhiyun Yang¹, Xiaoxiao Zhao², Yingxi Chen¹, and Mengzhu Wang³

¹The first affiliated hospital of sun yat-sen university, Guangzhou, China, ²The first affiliated hospital of sun yat-sen university, Guanzhou, China, ³MR Scientific Marketing, Siemens Healthineers Ltd, Guanzhou, China

Synopsis

Keywords: Muscle, MR Value, myasthenia gravis, TOF MRA, extraocular muscleThe study investigated the feasibility of TOF MAR sequence in evaluating extraocular muscle morphological changes in patients with myasthenia gravis. The results show that volume measurement of EOM based on TOF MRA imaging can effectively quantify atrophy of EOM in MG patients, which is significantly related to the poor response to medication and the long duration of the disease, meaning that it can be used as a non-invasive auxiliary diagnostic tool for prognosis evaluation of MG patients.

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