Abstract #4072

Design of calibration-free RF pulses for T2-weighted single-slab 3D turbo-spin-echo sequences at 7T utilizing parallel transmission

Daniel Löwen¹, Eberhard Daniel Pracht¹, Vincent Gras², Aurelien Massire³, Franck Mauconduit², Nicolas Boulant², and Tony Stöcker^1,4

¹German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, ²Université Paris-Saclay, Commissariat à l’Energie Atomique, CNRS, NeuroSpin, BAOBAB, Gif sur Yvette, France, ³Siemens Healthineers, Saint-Denis, France, ⁴Department of Physics and Astronomy, University of Bonn, Bonn, Germany

Synopsis

Keywords: High-Field MRI, RF Pulse Design & Fields, Brain, Parallel Transmit & MultibandMulti-Slice T2-weighted MR imaging is a fundamental technique in brain imaging but suffers from field inhomogeneities at ultra-high field systems. In this work we present a pulse design method which provides slab-selective universal pulses with phase-coherent excitation profiles over selected brain regions. Applied in a 3D variable flip angle turbo-spin-echo (TSE) sequence, the pulses achieve superior SNR compared to multi-slice TSE imaging and B1+ field inhomogeneity mitigation.

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