Abstract #4077

Background Field Inhomogeneity Correction for High-Resolution T2* Mapping of the Human Cervical Spinal Cord at 7T

Seyedeh Nasim Adnani^1,2, Sultan Zaman Mahmud^1,2, Thomas S. Denney^1,2, and Adil Bashir^1,2

¹Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, United States, ²Auburn University MRI Research Center, Auburn University, Auburn, AL, United States

Synopsis

Keywords: High-Field MRI, Spinal Cord, T2* mapping, ArtifactsUltra-high-field (UHF) Spinal Cord (SC) imaging could be helpful in detecting subtle pathological changes in the human SC. The increased effect of magnetic field inhomogeneity at UHF on T2* renders the quantification unreliable. Therefore, the field correction methods are critical. We have demonstrated the application of the Voxel Spread function method, to address this issue in human SC at 7T. F-term correction was applied to the pre-processed SC images, and the T2* values were reported for SC GM and WM both before and after field inhomogeneity correction. VSF reduces magnetic field inhomogeneity effects for quantitative T2* mapping in human SC.

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