Abstract #4089

Effects of spatial resolution on brain tissue displacement estimates based on DENSE MRI at 7T

Amelia Strom^1,2, Timothy G. Reese^2,3, Zijing Dong^2,3, Baarbod Ashenagar⁴, Laura D. Lewis^2,4, and Jonathan R. Polimeni^1,2,3

¹Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, ²Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ³Department of Radiology, Harvard Medical School, Boston, MA, United States, ⁴Department of Biomedical Engineering, Boston University, Boston, MA, United States

Synopsis

Keywords: High-Field MRI, Tissue Characterization, Neurofluids, Diffusion Imaging TechniquesDisplacement Encoding with Stimulated Echoes (DENSE) MRI was used to estimate pons and midbrain tissue displacement over the cardiac cycle at 2-mm, 3-mm, and 4-mm isotropic spatial resolutions in individual subjects at 7T. Displacement estimates were largest at 2-mm resolution and matched previous reports of peak brainstem displacement over the cardiac cycle. Smaller estimates at lower resolution may be due to partial volume effects from the surrounding tissue or CSF.

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