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Abstract #4094

3D Pulmonary Dynamic Ventilation Imaging with High Spatial and Temporal Resolution Using Hyperpolarized 129Xe MRI

Hongchuang Li1,2, Haidong Li1,2, Ming Zhang1,2, Xiaoling Liu1,2, Xiuchao Zhao1,2, Yeqing Han1,2, Chaohui Ye1,2, and Xin Zhou1,2
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences- Wuhan National Laboratory for Optoelectronics, Wuhan, China, 2University of Chinese Academy of Sciences, Beijing, China

Synopsis

Keywords: Pulse Sequence Design, Hyperpolarized MR (Gas)The mutual restriction of temporal and spatial resolution is a challenge for hyperpolarized gas dynamic MRI, especially for 3D acquisition. Herein, we proposed a methodology to image the pulmonary dynamic ventilation with high temporal and spatial resolution using hyperpolarized gas MRI based on a 3D gradient echo sequence. Furthermore, we observed the difference of pulmonary dynamic ventilation in the posterior-anterior direction.

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