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Abstract #4097

Effects of patch size on 3D patch-based super-resolution reconstruction of hyperpolarized 13C cardiac MRI

Sung-Han Lin1, Junjie Ma2, and JaeMo Park1,3
1Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, 2GE Healthcare, New York, NY, United States, 3Radiology, UT Southwestern Medical Center, Dallas, TX, United States

Synopsis

Keywords: Data Processing, CardiomyopathyThe volumetric patch-based super-resolution method can reconstruct a single-slice low-resolution hyperpolarized 13C MRI to multiple 13C slices with enhanced spatial resolution by exploiting the corresponding high-resolution structural 1H MRI. In this study, the overall performance of this method and the effects of patch size were evaluated using a simulated digital phantom and an anthropomorphic cardiac 13C MR phantom. The optimal patch size for this reconstruction method was also applied to in-vivo human 13C cardiac images acquired with an injection of hyperpolarized [1-13C]pyruvate.

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Keywords