Meeting Banner
Abstract #4099

Improved Dynamic In Vivo pH Imaging Using Hyperpolarized 13C-bicarbonate

Xiaoxi Liu1, Changhua Mu1, Ying-Chieh Lai1,2, Robert A. Bok1, Romelyn Delos Santos1, Yaewon Kim1, Avantika Sinha1, Jeremy Gordon1, Robert Flavell1, and Peder Larson1
1Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taiwan, Taiwan

Synopsis

Keywords: Data Acquisition, Hyperpolarized MR (Non-Gas)We present a dynamic pH measurement using metabolite-specific gradient-echo spiral sequence with flow suppression to improve the SNR of bicarbonate and CO2 with short T2* and used bipolar gradients to suppress the high bicarbonate signal in the vessel. With the improved image quality and high temporal resolution, it is possible to measure the dynamic pH in vivo. Future studies will work to increase the sample size to confirm these results.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract Presentation Video

Keywords