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Abstract #4101

Assessment of Pulmonary Morphometry using Hyperpolarized 129Xe DWI with Variable-Sampling-Ratio Compressed Sensing Patterns

Qian Zhou1,2, Haidong Li1,2, Qiuchen Rao1, Ming Zhang1,2, Xiuchao Zhao1,2, Luyang Shen1, Yuan Fang1, Hongchuang Li1,2, Xiaoling Liu1,2, Sa Xiao1,2, Lei Shi1,2, Yeqing Han1,2, Chaohui Ye1,2, and Xin Zhou1,2
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences- Wuhan National Laboratory for Optoelectronics, Wuhan, China, 2University of Chinese Academy of Sciences, Beijing, China

Synopsis

Keywords: Data Acquisition, Hyperpolarized MR (Gas)The long acquisition time of hyperpolarized 129Xe multiple b-values DWI made it hard to apply in patients with severe pulmonary diseases. Herein, we proposed a method of variable-sampling-ratio compressed sensing patterns for accelerating hyperpolarized 129Xe DWI. A four-fold reduction in acquisition time was achieved using the proposed method while preserving good image quality. Meanwhile, the method can be used for evaluating pulmonary injuries caused by cigarette smoking.

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