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Abstract #4108

Regional 17O T2* in Human Brain at 3T

Hao Song1, Hamidreza Saeidi1, Johannes Fisher1, Ali Caglar Özen1, Stefan Schumann2, and Michael Bock1
1Dept. of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 2Dept. of Anesthesiology and Critical Care, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Synopsis

Keywords: Data Analysis, Non-ProtonInformation about T2* relaxation time plays an important role in data acquisition for 17O-MRI. In this work, we investigated the in vivo T2* relaxation time constants of 17O in regional brain tissue at 3T. Overall, regional T2* relaxation times are in a range of 1.5 - 2ms (except for CSF). Additionally, a T2* variation of 0.12ms was found from superficial to deep layers in the insular cortex. Our results indicate that short-TE acquisition strategies are favorable for 17O-MRI of the brain.

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