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Abstract #4131

SSc primary heart involvement assessed by cardiovascular magnetic resonance imaging and explore its relationship with the skin involvement

Yanan Zhao1, Jianing Cui1, Xiuzheng Yue2, and Tao Li1
1Department of Radiology, The First Medical Center of PLA General Hospital, Beijing, China, 2Philips Healthcare(Beijing), Beijing, China

Synopsis

Keywords: Heart, Heart, SSc primary heart involvement, cardiovascular magnetic resonance,extracellular-volume fraction, modified Rodnan skin scoreCardiac involvement is a significant cause of morbidity and mortality in subclinical systemic sclerosis (SSc). There are, however, no effective methods for detecting cardiac involvement in a general, asymptomatic SSc cohort. We aim to characterize SSc-primary heart involvement (SSc-pHI) through cardiovascular magnetic resonance (CMR), exploring the relationship between SSc-pHI and skin involvement by modified Rodnan skin score (mRSS). We found that 71% of SSC patients had Late gadolinium enhancement (LGE) fibrosis, and 75% and 46% had anomalous native T1 and extracellular-volume fraction (ECV). In addition, SSc-pHI is related to the severity of skin involvement.

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