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Abstract #4136

MRI relaxometry mapping of hearts extracted post-mortem from acute COVID-19 patients

El-Sayed H. Ibrahim1, Andrii Puzyrenko1, and Ivor Benjamin1
1Medical College of Wisconsin, Milwaukee, WI, United States

Synopsis

Keywords: Myocardium, COVID-19Cardiac MRI is capable of myocardial tissue characterization using parametric mapping techniques such as T1 and T2 mappings, which are sensitive for detecting diffuse inflammation, fibrosis and edema. These techniques seem adequate for the detection of myocardial changes in COVID-19. In this study, we demonstrated the use of ex vivo MRI mapping techniques for noninvasive myocardial tissue characterization in COVID-19 patients and compared the MRI results to findings from autopsy reports. The proposed approach would allow for better understanding of COVID-19 pathophysiological effects on the myocardium through longitudinal studies that could be conducted without the need for invasive endomyocardial biopsy.

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Keywords