Abstract #4148
Developing and Evaluating a Chronic Ischemic Cardiomyopathy in Swine Model by Rest and Stress CMR
baiyan zhuang1, Minjie Lu2, jian he3, and jing xu2
1Department of Magnetic Resonance Imaging, Key Laboratory of Cardiovascular Imaging(cultivation) , Cardiovascular imaging and intervention Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2Department of Magnetic Resonance Imaging, Key Laboratory of Cardiovascular Imaging(cultivation) , Cardiovascular imaging and intervention Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, beijing, China, 3Department of Magnetic Resonance Imaging, Key Laboratory of Cardiovascular Imaging(cultivation) , Cardiovascular imaging and intervention Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, beijjing, China
Synopsis
Keywords: Myocardium, MR ValueThis preclinical study has established that chronic coronary artery stenosis can induce significant myocyte loss with modest global replacement fibrosis that leads to global LV dysfunction and varying degrees of congestive heart failure.
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