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Abstract #4164

Feasibility of spiral diffusion imaging on a clinical 3T MR system

Lars Kasper1, Zhe Wu1, Alexander Jaffray1,2, Sriranga Kashyap1, and Kamil Uludag1,3,4
1BRAIN-TO Lab, Techna Institute, University Health Network, Toronto, ON, Canada, 2UBC MRI Research Centre, Vancouver, BC, Canada, 3Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, 4Center for Neuroscience Imaging Research, Institute for Basic Science & Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of

Synopsis

Keywords: Diffusion/other diffusion imaging techniques, Diffusion Tensor Imaging, Spiral DWISpiral diffusion imaging has been shown to provide substantial SNR advantages (>50%) over state-of-the-art echo-planar imaging, due to the attainable shorter echo times. We investigate the feasibility of this approach on a standard 3T MR system without additional instrumentation. All tools for successful implementation are freely made available, i.e., the characterization measurement for the gradient system using a standard phantom, and an open-source, fast image reconstruction suite in Julia correcting for gradient imperfections, eddy currents, and static B0 off-resonance. We show that this low-cost, accessible solution provides high-resolution diffusion images (1.1mm) in-vivo with reduced geometric distortion and improved quantitative maps.

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