Abstract #4170

Feasibility and Preliminary Evaluation of Breath Hold and Free Breathing Quantitative Susceptibility Mapping of the Liver

Julia V Velikina¹, Collin J Buelo^1,2, Yan Wu³, Marcus T Alley³, Moniba Nazeef⁴, Michael Jeng³, Alexey A Samsonov¹, Scott B Reeder^1,2,4,5,6, Shreyas S Vasanawala³, and Diego Hernando^1,2

¹Radiology, University of Wisconsin - Madison, Madison, WI, United States, ²Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, ³Stanford University, Stanford, CA, United States, ⁴Medicine, University of Wisconsin - Madison, Madison, WI, United States, ⁵Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States, ⁶Emergency Medicine, University of Wisconsin - Madison, Madison, WI, United States

Synopsis

Keywords: Susceptibility, LiverQuantitative susceptibility mapping (QSM) is a promising non-invasive technique for quantification of liver iron concentration. Abdominal QSM typically requires a breath-hold acquisition since respiration induces liver motion, which leads to blurring artifacts. However, some patients have trouble even with a short breath-hold, which necessitates development of free-breathing approaches. In this work, we report initial results on the feasibility of using the modified “butterfly” navigator approach in multi-echo imaging in conjunction with compressed sensing reconstruction to enable free-breathing liver QSM.

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