Meeting Banner
Abstract #4172

Subject-specific χ-separation method: the effect of introducing a personalised relaxometric constant Dr

Elena Grosso1, Antonio Ricciardi2, Egidio D'Angelo1,3, Fulvia Palesi1, and Claudia AM Gandini Wheeler-Kingshott1,2,3
1Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy, 2NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom, 3Brain Connectivity Centre Research Unit, IRCCS Mondino Foundation, Pavia, Italy

Synopsis

Keywords: Susceptibility, Modelling, Brain

χ-separation is a recently proposed biophysical model to separate the χ-positive and χ-negative contribution of magnetic susceptibility sources in the brain. Such a model relies on assuming a certain relaxometric constant (Dr) calculated as the mean of a group of healthy subjects. Here we demonstrate that Dr is subject-specific and if used in place of the average value, it affects the χ-positive and χ-negative maps in a structured way, while their sum remains similar.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract Presentation Video

Keywords