Abstract #4186

Dynamic Geometric Distortion Correction for Quantitative Susceptibility Mapping Using a Multi-Echo 2D-EPI Sequence

Oliver C. Kiersnowski¹, Patrick Fuchs¹, Stephen J. Wastling^2,3, John S. Thornton^2,3, and Karin Shmueli¹

¹Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom, ²Neuroradiological Academic Unit, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom, ³Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom

Synopsis

Keywords: Susceptibility, Quantitative Susceptibility mappingEcho planar imaging (EPI) suffers from geometric distortions, which can be corrected using reference acquisitions for single-echo EPI, or using field maps calculated from the multiple echoes in multi-echo EPI. The effect of distortion on EPI quantitative susceptibility mapping (QSM) has not been investigated. We compared static and dynamic geometric distortion correction for magnitude images and QSM using multi-echo 2D-EPI acquisitions with and without changes in head position. Multi-echo EPI corrected distortion in both magnitude and QSM images without the need for reference scans. Correcting the local field map in the QSM pipeline was optimal to reduce temporal variance.

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