Keywords: Muscle, Muscle, muscular dystrophyBoth MRI and MRS measures reveal that water T2 can be elevated in individuals living with dystrophin deficits, which includes patients with DMD, BMD and manifesting carriers. This has important implications when evaluating therapeutics aimed at decreasing inflammation (e.g., corticosteroids or NFkb inhibitors) or disease modifying interventions, such as gene therapies.
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