Abstract #4212

Quantification of lumbar paraspinal muscle injury in patients with low back pain using intravoxel incoherent motion diffusion weighted imaging

Yinqi Liu¹, Weiyin Vivian Liu², and Kun Zhang^1,3

¹Department of Radiology, First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China, ²MR Research, GE Healthcare, Beijing, China, ³College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, China

Synopsis

Keywords: Muscle, Diffusion/other diffusion imaging techniquesChronic low back pain (CLBP) has been reported to be associated with lumbar paraspinal muscles injury. Lumbar paraspinal muscles injury may result from oxidative stress and inflammation. In our study, D* at the middle of L4 and L5 levels of the paraspinal muscles was significantly higher in LBP group than in HCs. The fluid oozing from the inflammation can lead to greater unrestricted molecular movement. Therefore, non-invasive and contrast-agent-free IVIM could be a good perfusion predictor of lumbar paraspinal muscle injury.

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