Abstract #4213

Exercise-induced changes of macromolecular content in calf muscles quantified with T1ρ magnetic resonance imaging

Yanbin Li^1,2, Chang Ni², Jialin Wang¹, Zhenfeng Lv^3,4, Xin Mu², Mingyan Wu¹, Haikun Qi^3,4, and Jeff L. Zhang²

¹Central Research Institute, Shanghai United Imaging Healthcare Co., Ltd, Shanghai, China, ²Vascular and Physiologic Imaging Research (VPIR) Lab, School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, ³School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, ⁴Shanghai Clinical Research and Trial Center, Shanghai, China

Synopsis

Keywords: Muscle, Quantitative Imaging

Exercise could induce changes in skeletal muscle’s macromolecular content. In this study, we used an exercise-then-imaging protocol to verify and characterize such phenomenon for calf muscles of healthy subject. A T1ρ mapping technique was used for imaging calf muscles before and after planter flexion of different loads. It was found that post-exercise increases in T1ρ values of gastrocnemius and peroneus longus at exercise load of 16 and of 20 lbs were significantly higher than that of 8 lbs. In conclusion, T1ρ is sensitive to changes of macromolecular content in calf muscles induced by plantar flexion of moderate or high intensity.

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