Abstract #4224

Magnetic resonance fingerprinting thermometry (MRFT) versus PRFS thermometry: comparative temperature prediction in ex vivo bovine muscle

Enlin Qian¹, Pavan Poojar², Maggie Fung³, Zhezhen Jin⁴, John Thomas Vaughan¹, Devashish Shrivastava¹, David Gultekin¹, and Sairam Geethanath²

¹Columbia Magnetic Resonance Research Center, Columbia University, New York, NY, United States, ²Accessible MR Laboratory, Biomedical Engineering and Imaging Institute, Dept. of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mt. Sinai, New York, NY, United States, ³GE Healthcare, New York, NY, United States, ⁴Department of Biostatistics, Columbia University, New York, NY, United States

Synopsis

Keywords: Safety, SafetyWe explored T₁-based magnetic resonance fingerprinting thermometry (MRFT) and compared it with proton resonance frequency shift (PRFS) thermometry in ex vivo bovine muscle data. We conducted temperature sensitivity calibration experiments for both methods. We compared MRFT and PRFS thermometry predicted temperatures in bovine muscles, validated by fluoroptic probe measurements. We observed strong correlation in temperature sensitivity calibration experiments (R²>0.958). Both methods predict temperature accurately (RMSE<1.37 ℃ and RMSE<0.93 ℃ for MRFT and PRFS, over a range of 25 ℃). We observed strong correlation between PRFS and MRFT predicted temperature in heated bovine muscle (R²>0.93).

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