Abstract #4274

APTw Combined With Multiple Models DWI of Endometrial Cancer: Correlations Between Multimodal Parameters and HIF-1α Expression

Ma Changjun¹, Tian Shifeng¹, Liu Ailian¹, Chen Lihua¹, Lin Liangjie², Zhang Xiaoxiao³, Guo Yinghua⁴, and Wang Jiazheng⁴

¹Department of Radiology,, The First Affiliated Hospital of Dalian Medical University, Dalian, China, China, ²Clinical & Technical Support, Philips Healthcare, Beijing, China, China, ³Clinical & Technical Support, Philips Healthcare, Wuhan, China, China, ⁴Clinical & Technical Support, Philips Healthcare, Shanghai, China, China

Synopsis

Keywords: Placenta, Quantitative ImagingHIF-1α is a major transcriptional factor regulating gene expression under hypoxic conditions. The identification of HIF-1α expression is very helpful for the quantitative assessment of tumor hypoxia, on which the therapeutic response is predicted or regimens are adjusted .

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